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ONTOLOGY REPORT - ANNOTATIONS

Term:endoplasmic reticulum quality control compartment
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Accession:GO:0044322 term browser browse the term
Definition:A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins.
Synonyms:exact_synonym: ER quality control compartment;   ERQC
 related_synonym: ER-derived quality control compartment

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endoplasmic reticulum quality control compartment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asgr2 asialoglycoprotein receptor 2 located_in ISO (PMID:11408579) UniProt PMID:11408579 NCBI chrNW_004624786:9,728,949...9,753,438
Ensembl chrNW_004624786:9,728,336...9,753,434 		JBrowse link
G Calr calreticulin located_in ISO (MGI:6120598|PMID:11408579) UniProt PMID:11408579 MGI:6120598 NCBI chrNW_004624901:511,295...515,208
Ensembl chrNW_004624901:511,052...516,757 		JBrowse link
G Canx calnexin located_in ISO (MGI:6120598|PMID:11408579) UniProt PMID:11408579 MGI:6120598 NCBI chrNW_004624733:42,588,680...42,616,624 JBrowse link
G Derl1 derlin 1 located_in ISO (MGI:6467686|PMID:23233672) UniProt PMID:23233672 MGI:6467686 NCBI chrNW_004624735:31,832,711...31,857,687
Ensembl chrNW_004624735:31,832,701...31,857,687 		JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 located_in ISO (PMID:23233672) UniProt PMID:23233672 NCBI chrNW_004624773:15,846,347...15,878,312
Ensembl chrNW_004624773:15,846,553...15,878,803 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 located_in ISO (MGI:6467680|PMID:17707796) UniProt PMID:17707796 MGI:6467680 NCBI chrNW_004624749:15,867,444...15,950,757
Ensembl chrNW_004624749:15,869,569...15,950,757 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 located_in ISO (MGI:6467680|PMID:17707796) UniProt PMID:17707796 MGI:6467680 NCBI chrNW_004624782:8,823,114...8,840,073
Ensembl chrNW_004624782:8,823,146...8,840,280 		JBrowse link
G Fbxo6 F-box protein 6 located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624818:1,286,819...1,292,565
Ensembl chrNW_004624818:1,286,820...1,292,755 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624746:29,069,995...29,081,085
Ensembl chrNW_004624746:29,068,350...29,081,085 		JBrowse link
G Man1b1 mannosidase alpha class 1B member 1 located_in ISO (PMID:18003979) ParkinsonsUK-UCL PMID:18003979 NCBI chrNW_004624760:813,657...826,020
Ensembl chrNW_004624760:813,045...825,153 		JBrowse link
G Rhbdd1 rhomboid domain containing 1 located_in ISO (MGI:5437551|PMID:22795130) UniProt PMID:22795130 MGI:5437551 NCBI chrNW_004624843:1,217,655...1,362,406
Ensembl chrNW_004624843:1,219,808...1,360,135 		JBrowse link
G Sec61b SEC61 translocon subunit beta located_in ISO (PMID:17707796)
(MGI:6120598|PMID:11408579), (MGI:6467680|PMID:17707796)		 UniProt PMID:11408579 PMID:17707796 MGI:6120598 MGI:6467680 NCBI chrNW_004624825:1,762,735...1,771,271
Ensembl chrNW_004624825:1,762,734...1,771,233 		JBrowse link
G Syvn1 synoviolin 1 located_in ISO (MGI:6467680|PMID:17707796)
(PMID:23233672), (PMID:24478453)		 UniProt PMID:17707796 PMID:23233672 PMID:24478453 MGI:6467680 NCBI chrNW_004624767:21,269,909...21,276,739
Ensembl chrNW_004624767:21,270,841...21,275,653 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 15721
    cellular anatomical entity 15623
      endoplasmic reticulum quality control compartment 13
Path 2
Term Annotations click to browse term
  cellular_component 15721
    cellular anatomical entity 15623
      organelle 11370
        membrane-bounded organelle 10395
          intracellular membrane-bounded organelle 9903
            endoplasmic reticulum 1490
              endoplasmic reticulum quality control compartment 13
paths to the root